(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic, and anti-microbial effects. It acts as an inhibitor of COX-1 and COX-2 enzymes in vitro, with IC50 values of 1.12 μM and 0.83 μM, respectively. The product is intended for research use only and is not sold to patients.
- Natural product sourced from Kaempferia galangal.
- Exhibits anti-inflammatory, anti-neoplastic, and anti-microbial effects.
- Inhibits COX-1 (IC50: 1.12 μM) and COX-2 (IC50: 0.83 μM) in vitro.
- Shows moderate inhibitory activity against α-glucosidase (IC50: 50 μM).
- Inhibits migration and tubular structure formation in HUVECs.
- Exhibits cytotoxicity in various cancer cells.
- Induces apoptosis through caspase-3/7/8/9 activation in cancer cells.
- Inhibits bFGF and heparin-induced angiogenesis.